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Lesson 5 Assignment

L. R. Schaeffer, March 1999

Using simulation, generate
one hundred, 100, males from a population which had
frequencies of
*p*_{A}=0.6 for
and *p*_{B}=0.2 for
,
and 100 females from a population with
frequencies of *p*_{A}=0.3 and *p*_{B}=0.7.
Mate each male and female only once to produce one offspring.
Assume that *a*_{A}=2, *a*_{B}=1, *d*_{A}=0, and *d*_{B}=0.

- 1.
- Calculate the expected and actual frequencies of all
9 possible genotypes
in the progeny generation.

- 2.
- Estimate the gene frequencies at each locus from the
actual data in the
progeny generation.

- 3.
- Calculate the amount of joint disequilibrium in
the progeny generation by comparing actual gamete
frequencies to expected gamete frequencies.

- 4.
- Calculate the genetic variance at each locus separately
and for both loci together
using the actual data (not estimated frequencies),
then verify that

- 5.
- Repeat the step 4 with
*d*_{A}=1 and*d*_{B}=-0.5.